# PICOT Question

PICOT Question

In adult sickle anemia patients, does the use of morphine in addition to NSAIDS decrease chronic pain compared to NSAIDS alone?

Population: Adult sickle cell Anemia patients (<50yrs)

Intervention: The use of morphine in addition to NSAIDS during Chronic pain

Comparison: The use of only NSAIDS

Outcome: Understand if the addition of morphine decreases chronic pain during sickle cell crisis.

Time: One year

References

Geller, & O’Connor. (2008). The sickle cell crisis: a dilemma in pain relief. Mayo Clinic Proc , 83:320-323.

Rees, Williams, & Gladwin. (2010). Sickle-cell disease. . Lancet , 376(9757); 2018-2031

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